Conductance Mechanisms of Rapidly Desensitizing Cation Channelrhodopsins from Cryptophyte Algae

ABSTRACT Channelrhodopsins guide algal phototaxis and are widely used as optogenetic probes for control of membrane potential with light. “Bacteriorhodopsin-like” cation channelrhodopsins (BCCRs) from cryptophytes differ in primary structure from other CCRs, lacking usual residues important for thei...

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Bibliographic Details
Main Authors: Oleg A. Sineshchekov, Elena G. Govorunova, Hai Li, Yumei Wang, Michael Melkonian, Gane K.-S. Wong, Leonid S. Brown, John L. Spudich
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00657-20