Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells

High Mobility Group AT-hook 2 (HMGA2) is a nonhistone chromatin-binding protein which acts as a transcriptional regulating factor involved in gene transcription. In particular, overexpression of HMGA2 has been demonstrated to associate with neoplastic transformation and tumor progression in Colorect...

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Bibliographic Details
Main Authors: Chun-Yu Kao, Pei-Ming Yang, Ming-Heng Wu, Chi-Chen Huang, Yi-Chao Lee, Kuen-Haur Lee
Format: Article
Language:English
Published: PeerJ Inc. 2016-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1683.pdf