Intracellular functions and motile properties of bi-directional kinesin-5 Cin8 are regulated by neck linker docking
In this study, we analyzed intracellular functions and motile properties of neck-linker (NL) variants of the bi-directional S. cerevisiae kinesin-5 motor, Cin8. We also examined – by modeling – the configuration of H-bonds during NL docking. Decreasing the number of stabilizing H-bonds resulted in p...
Main Authors: | Alina Goldstein-Levitin, Himanshu Pandey, Kanary Allhuzaeel, Itamar Kass, Larisa Gheber |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/71036 |
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