OpenVar: functional annotation of variants in non-canonical open reading frames

Abstract Background Recent technological advances have revealed thousands of functional open reading frames (ORF) that have eluded reference genome annotations. These overlooked ORFs are found throughout the genome, in any reading frame of transcripts, mature or non-coding, and can overlap annotated...

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Bibliographic Details
Main Authors: Marie A. Brunet, Sébastien Leblanc, Xavier Roucou
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-022-00871-x