Neuropeptide-Functionalized Gold Nanorod Enhanced Cellular Uptake and Improved In Vitro Photothermal Killing in LRP1-Positive Glioma Cells

Neuropeptide-Functionalized Gold Nanorod Enhanced Cellular Uptake and Improved In Vitro Photothermal Killing in LRP1-Positive Glioma Cells

The therapeutic modalities for glioblastoma multiforme fail badly due to the limitations of poor penetration through the blood–brain barrier and the lack of tumor targeting. In this study, we synthesized a neuropeptide (ANGIOPEP-2)-functionalized gold nanorod (GNR-ANGI-2) and systemically evaluated...

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Bibliographic Details
Main Authors: Siva Sankari Sivasoorian, Ritesh Urade, Chien-Chih Chiu, Li-Fang Wang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
glioma
blood–brain barrier
neuropeptide (ANGIOPEP-2)
gold nanorod
photothermal therapy
hyperthermia
Online Access:https://www.mdpi.com/1999-4923/14/9/1939

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https://www.mdpi.com/1999-4923/14/9/1939

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