Determination of the urinary aglycone metabolites of vitamin K by HPLC with redox-mode electrochemical detection

Determination of the urinary aglycone metabolites of vitamin K by HPLC with redox-mode electrochemical detection

We describe a method for the determination of the two major urinary metabolites of vitamin K as the methyl esters of their aglycone structures, 2-methyl-3-(3′-3′-carboxymethylpropyl)-1,4-naphthoquinone (5C-aglycone) and 2-methyl-3-(5′-carboxy-3′-methyl-2′-pentenyl)-1,4-naphthoquinone (7C-aglycone),...

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Bibliographic Details
Main Authors: Dominic J. Harrington, Robin Soper, Christine Edwards, Geoffrey F. Savidge, Stephen J. Hodges, Martin J. Shearer
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
phylloquinone
menaquinones
urinary vitamin K metabolites
aglycones
high-performance liquid chromatography with electrochemical detection
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339894

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http://www.sciencedirect.com/science/article/pii/S0022227520339894

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