3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
Abstract Background State‐of‐the‐art 3‐dimensional (3D) electron microscopy approaches provide a new standard for the visualization of human platelet ultrastructure. Application of these approaches to platelets rapidly fixed prior to purification to minimize activation should provide new insights in...
Main Authors: | Irina D. Pokrovskaya, Shilpi Yadav, Amith Rao, Emma McBride, Jeffrey A. Kamykowski, Guofeng Zhang, Maria A. Aronova, Richard D. Leapman, Brian Storrie |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Research and Practice in Thrombosis and Haemostasis |
Subjects: | |
Online Access: | https://doi.org/10.1002/rth2.12260 |
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