Epigenetic Dysregulation of <i>KCNK9</i> Imprinting and Triple-Negative Breast Cancer

Epigenetic Dysregulation of <i>KCNK9</i> Imprinting and Triple-Negative Breast Cancer

Genomic imprinting is an inherited form of parent-of-origin specific epigenetic gene regulation that is dysregulated by poor prenatal nutrition and environmental toxins. <i>KCNK9</i> encodes for TASK3, a pH-regulated potassium channel membrane protein that is overexpressed in 40% of brea...

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Bibliographic Details
Main Authors: David A. Skaar, Eric C. Dietze, Jackelyn A. Alva-Ornelas, David Ann, Dustin E. Schones, Terry Hyslop, Christopher Sistrunk, Carola Zalles, Adrian Ambrose, Kendall Kennedy, Ombeni Idassi, Gustavo Miranda Carboni, Michael N. Gould, Randy L. Jirtle, Victoria L. Seewaldt
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
triple negative breast cancer
<i>KCNK9</i>
epigenetics
imprinting
Online Access:https://www.mdpi.com/2072-6694/13/23/6031

Internet

https://www.mdpi.com/2072-6694/13/23/6031

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