Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury

Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury

Mitochondrial dysfunction is a fundamental challenge in septic cardiomyopathy. Mitophagy and the mitochondrial unfolded protein response (UPRmt) are the predominant stress-responsive and protective mechanisms involved in repairing damaged mitochondria. Although mitochondrial homeostasis requires the...

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Bibliographic Details
Main Authors: Yue Wang, Heinrich Jasper, Sam Toan, David Muid, Xing Chang, Hao Zhou
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Redox Biology
Subjects:
Mitophagy
Mitochondrial unfolded protein response
Septic cardiomyopathy
Inflammation
FUN14 domain-containing 1
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002081

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http://www.sciencedirect.com/science/article/pii/S2213231721002081

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