A multi‐omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells

A multi‐omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells

Abstract Although cancer‐derived extracellular vesicles (cEVs) are thought to play a pivotal role in promoting cancer progression events, their precise effect on neighbouring normal cells is unknown. In this study, we investigated the impact of pancreatic cancer ductal adenocarcinoma (PDAC) derived...

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Bibliographic Details
Main Authors: Charles P. Hinzman, Baldev Singh, Shivani Bansal, Yaoxiang Li, Anton Iliuk, Michael Girgis, Kelly M. Herremans, Jose G. Trevino, Vijay K. Singh, Partha P. Banerjee, Amrita K. Cheema
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Journal of Extracellular Vesicles
Subjects:
ER stress
extracellular vesicles
multi‐omics
pancreatic cancer
Online Access:https://doi.org/10.1002/jev2.12232

Internet

https://doi.org/10.1002/jev2.12232

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