Impact of IgG Isotype on the Induction of Antibody-Dependent Cellular Phagocytosis of HIV by Human Milk Leukocytes

Impact of IgG Isotype on the Induction of Antibody-Dependent Cellular Phagocytosis of HIV by Human Milk Leukocytes

Approximately 100,000 mother-to-child transmission (MTCT) events of HIV via human milk feeding occur each year. However, only about 15% of infants milk-fed by untreated HIV+ mothers become infected, suggesting a protective effect of the milk itself. Infants ingest 105-108 maternal leukocytes daily v...

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Bibliographic Details
Main Authors: Alisa Fox, Xiaomei Liu, Susan Zolla-Pazner, Rebecca L. Powell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
human milk
lactation
ADCP
phagocytosis
mother-to-child HIV transmission
HIV
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.831767/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.831767/full

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