Questioning the role of palmitoylethanolamide in psychosis: a systematic review of clinical and preclinical evidence

Questioning the role of palmitoylethanolamide in psychosis: a systematic review of clinical and preclinical evidence

IntroductionThe endocannabinoid (eCB) system disruption has been suggested to underpin the development of psychosis, fueling the search for novel, better-tolerated antipsychotic agents that target the eCB system. Among these, palmitoylethanolamide (PEA), an N-acylethanolamine (AE) with neuroprotecti...

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Bibliographic Details
Main Authors: Riccardo Bortoletto, Fabiana Piscitelli, Anna Candolo, Sagnik Bhattacharyya, Matteo Balestrieri, Marco Colizzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Psychiatry
Subjects:
Schizophrenia
bipolar disorder
major depressive disorder
antipsychotics
cannabidiol
nutraceuticals
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1231710/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1231710/full

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