Structural and Biophysical Insights into the TCRαβ Complex in Chickens
Summary: In this work, chicken HPAIV H5N1 epitope-specific TCRαβ (ch-TCRαβ) was isolated and its structure was determined. The Cα domain of ch-TCRαβ does not exhibit the typical structure of human TCRαβ, and the DE loop extends outward, resulting in close proximity between the Cα domain of ch-TCRαβ...
Prif Awduron: | , , , , , |
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Fformat: | Erthygl |
Iaith: | English |
Cyhoeddwyd: |
Elsevier
2020-12-01
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Cyfres: | iScience |
Pynciau: | |
Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S2589004220310257 |