Structural and Biophysical Insights into the TCRαβ Complex in Chickens

Summary: In this work, chicken HPAIV H5N1 epitope-specific TCRαβ (ch-TCRαβ) was isolated and its structure was determined. The Cα domain of ch-TCRαβ does not exhibit the typical structure of human TCRαβ, and the DE loop extends outward, resulting in close proximity between the Cα domain of ch-TCRαβ...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lijie Zhang, Yanjie Liu, Geng Meng, Ruiying Liang, Bing Zhang, Chun Xia
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2020-12-01
Cyfres:iScience
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2589004220310257