The Key Differences between Human Papillomavirus-Positive and -Negative Head and Neck Cancers: Biological and Clinical Implications

The Key Differences between Human Papillomavirus-Positive and -Negative Head and Neck Cancers: Biological and Clinical Implications

Head and neck squamous cell carcinoma (HNSCC) is a unique malignancy associated with two distinct risk factors: exposure to typical carcinogens and infection of human papillomavirus (HPV). HPV encodes the potent oncoproteins E6 and E7, which bypass many important oncogenic processes and result in ca...

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Bibliographic Details
Main Authors: Steven F. Powell, Lexi Vu, William C. Spanos, Dohun Pyeon
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
head and neck cancer
head and neck squamous cell carcinoma
human papillomavirus
treatment
clinical outcome
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/20/5206

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https://www.mdpi.com/2072-6694/13/20/5206

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