Validation of polymorphic Gompertzian model of cancer through in vitro and in vivo data.

Mathematical modeling plays an important role in our understanding and targeting therapy resistance mechanisms in cancer. The polymorphic Gompertzian model, analyzed theoretically and numerically by Viossat and Noble to demonstrate the benefits of adaptive therapy in metastatic cancer, describes a h...

Full description

Bibliographic Details
Main Authors: Arina Soboleva, Artem Kaznatcheev, Rachel Cavill, Katharina Schneider, Kateřina Staňková
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310844