Redox-sensitivity and site-specificity of S- and N- denitrosation in proteins.

S-nitrosation--the formation of S-nitrosothiols (RSNOs) at cysteine residues in proteins--is a posttranslational modification involved in signal transduction and nitric oxide (NO) transport. Recent studies would also suggest the formation of N-nitrosamines (RNNOs) in proteins in vivo, although their...

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Bibliographic Details
Main Authors: Frances L Jourd'heuil, Anthony M Lowery, Elaina M Melton, Sanie Mnaimneh, Nathan S Bryan, Bernadette O Fernandez, Joo-Ho Park, Chung-Eun Ha, Nadhipuram V Bhagavan, Martin Feelisch, David Jourd'heuil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3006389?pdf=render