Measurement of Patient-Derived Glioblastoma Cell Response to Temozolomide Using Fluorescence Lifetime Imaging of NAD(P)H

Measurement of Patient-Derived Glioblastoma Cell Response to Temozolomide Using Fluorescence Lifetime Imaging of NAD(P)H

Personalized strategies in glioblastoma treatment are highly necessary. One of the possible approaches is drug screening using patient-derived tumor cells. However, this requires reliable methods for assessment of the response of tumor cells to treatment. Fluorescence lifetime imaging microscopy (FL...

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Bibliographic Details
Main Authors: Diana V. Yuzhakova, Daria A. Sachkova, Marina V. Shirmanova, Artem M. Mozherov, Anna V. Izosimova, Anna S. Zolotova, Konstantin S. Yashin
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceuticals
Subjects:
glioblastoma
personalized therapy
patient-derived cell culture
fluorescence lifetime imaging FLIM
metabolism
NAD(P)H
Online Access:https://www.mdpi.com/1424-8247/16/6/796

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https://www.mdpi.com/1424-8247/16/6/796

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