Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light

Abstract Optogenetics enables precise regulation of intracellular signaling in target cells. However, the application of optogenetics to induce the differentiation of precursor cells and generate mature cells with specific functions has not yet been fully explored. Here, we focused on osteoclasts, w...

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Bibliographic Details
Main Authors: Aiko Takada, Toshifumi Asano, Ken-ichi Nakahama, Takashi Ono, Takao Nakata, Tomohiro Ishii
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52056-w