Engineered Bacteriophages Containing Anti-CRISPR Suppress Infection of Antibiotic-Resistant P. aeruginosa

Engineered Bacteriophages Containing Anti-CRISPR Suppress Infection of Antibiotic-Resistant P. aeruginosa

ABSTRACT The therapeutic use of bacteriophages (phages) provides great promise for treating multidrug-resistant (MDR) bacterial infections. However, an incomplete understanding of the interactions between phages and bacteria has negatively impacted the application of phage therapy. Here, we explored...

Full description

Bibliographic Details
Main Authors: Shugang Qin, Yongan Liu, Yuting Chen, Jinrong Hu, Wen Xiao, Xiaoshan Tang, Guohong Li, Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Aixin Yan, Khan Nadeem, Zhenwei Xia, Min Wu
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
P. aeruginosa
bacteriophages
CRISPR-Cas
Acr
multidrug resistance bacterial infection
anti-CRISPR
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01602-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01602-22

Similar Items