Steady State Kinetics for Enzymes with Multiple Binding Sites Upstream of the Catalytic Site

Steady State Kinetics for Enzymes with Multiple Binding Sites Upstream of the Catalytic Site

The Michaelis–Menten mechanism, which describes the binding of a substrate to an enzyme, is a simplification of the process on a molecular scale. A more detailed model should include the binding of the substrate to precatalytic binding sites (PCBSs) prior to the transition to the catalytic site. Our...

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Bibliographic Details
Main Authors: Manuel I. Osorio, Mircea Petrache, Dino G. Salinas, Felipe Valenzuela-Ibaceta, Fernando González-Nilo, William Tiznado, José M. Pérez-Donoso, Denisse Bravo, Osvaldo Yáñez
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Symmetry
Subjects:
steady-state enzyme kinetics
multi-precatalytic binding sites
numerical simulation
Online Access:https://www.mdpi.com/2073-8994/15/12/2176

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https://www.mdpi.com/2073-8994/15/12/2176

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