Mitochondrial mRNA localization is governed by translation kinetics and spatial transport.

For many nuclear-encoded mitochondrial genes, mRNA localizes to the mitochondrial surface co-translationally, aided by the association of a mitochondrial targeting sequence (MTS) on the nascent peptide with the mitochondrial import complex. For a subset of these co-translationally localized mRNAs, t...

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Bibliographic Details
Main Authors: Ximena G Arceo, Elena F Koslover, Brian M Zid, Aidan I Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010413