Discordance of KRAS Mutational Status between Primary Tumors and Liver Metastases in Colorectal Cancer: Impact on Long-Term Survival Following Radical Resection

Discordance of KRAS Mutational Status between Primary Tumors and Liver Metastases in Colorectal Cancer: Impact on Long-Term Survival Following Radical Resection

If KRAS mutation status of primary colorectal tumor is representative of corresponding colorectal liver metastases (CRLM) mutational pattern, is controversial. Several studies have reported different rates of KRAS discordance, ranging from 4 to 32%. Aim of this study is to assess the incidence of di...

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Bibliographic Details
Main Authors: Francesco Ardito, Francesco Razionale, Lisa Salvatore, Tonia Cenci, Maria Vellone, Michele Basso, Elena Panettieri, Maria Alessandra Calegari, Giampaolo Tortora, Maurizio Martini, Felice Giuliante
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
KRAS mutation status
KRAS discordance
precision medicine
colorectal tumor
colorectal liver metastases
overall survival
Online Access:https://www.mdpi.com/2072-6694/13/9/2148

Internet

https://www.mdpi.com/2072-6694/13/9/2148

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