Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2

Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2

The mechanisms underlying the neuroprotective effects of the hybrid antioxidant-nitric oxide donating compound SA-2 in retinal ganglion cell (RGC) degeneration models were evaluated. The in vitro trophic factor (TF) deprivation model in primary rat RGCs and ex vivo human retinal explants were used t...

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Bibliographic Details
Main Authors: Jennifer H. Pham, Gretchen A. Johnson, Rajiv S. Rangan, Charles E. Amankwa, Suchismita Acharya, Dorota L. Stankowska
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
neuroprotection
glaucoma
retinal ganglion cells
oxidative stress
neurotrophic factor
apoptosis
Online Access:https://www.mdpi.com/2073-4409/11/23/3741

Internet

https://www.mdpi.com/2073-4409/11/23/3741

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