Anxiolytic-like effects of Pseudospondias microcarpa hydroethanolic leaf extract in zebrafish: Possible involvement of GABAergic and serotonergic pathways

Anxiolytic-like effects of Pseudospondias microcarpa hydroethanolic leaf extract in zebrafish: Possible involvement of GABAergic and serotonergic pathways

Abstract Pseudospondias microcarpa is used in ethnomedicine to manage central nervous system diseases. The hydroethanolic extract (PME) from the leaves of the plant has shown anxiolytic-like properties in mice anxiety models. However, its effects in chronic anxiety models and possible mechanism(s) o...

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Bibliographic Details
Main Authors: Donatus Wewura Adongo, Charles Kwaku Benneh, Augustine Tandoh, Robert Peter Biney, Kennedy Kwami Edem Kukuia, Priscilla Kolibea Mante, Benjamin Kingsley Harley, David Oteng, Emmanuel Aduboffour Appiah, Ernest Cudjoe Anorbor, Eric Woode
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:Natural Products and Bioprospecting
Subjects:
Anxiety disorders
Pseudospondias microcarpa
Zebrafish
Novel tank
Benzodiazepines
Online Access:https://doi.org/10.1007/s13659-023-00399-8

Internet

https://doi.org/10.1007/s13659-023-00399-8

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