Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L

Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L

In this work, we investigated Diospyros kaki extract and an isolated compound for their potential as xanthine oxidase (XO) inhibitors, a target enzyme involved in inflammatory disorders. The prepared extract was subjected to column chromatography, and dinaphthodiospyrol S was isolated. Then XO inhib...

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Bibliographic Details
Main Authors: Tareq Abu-Izneid, Abdur Rauf, Zubair Ahmad, Abdul Wadood, Khurshid Ayub, Naveed Muhammad, Yahya S. Al-Awthan, Maria Maqbool, Omar S. Bahattab, Hassan A. Hemeg, Saima Naz, Dorota Formanowicz
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Diospyros kaki
Extract
dinaphthodiospyrol S
Xanthine oxidase activity
Docking analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423004310

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http://www.sciencedirect.com/science/article/pii/S1319016423004310

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