Glimepiride-Loaded Nanoemulgel; Development, In Vitro Characterization, Ex Vivo Permeation and In Vivo Antidiabetic Evaluation

Glimepiride-Loaded Nanoemulgel; Development, In Vitro Characterization, Ex Vivo Permeation and In Vivo Antidiabetic Evaluation

Glimepiride (GMP), an oral hypoglycemic agent is extensively employed in the treatment of type 2 diabetes. Transdermal delivery of GMP has been widely investigated as a promising alternative to an oral approach but the delivery of GMP is hindered owing to its low solubility and permeation. The prese...

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Bibliographic Details
Main Authors: Fizza Abdul Razzaq, Muhammad Asif, Sajid Asghar, Muhammad Shahid Iqbal, Ikram Ullah Khan, Salah-Ud-Din Khan, Muhammad Irfan, Haroon Khalid Syed, Ahmed Khames, Hira Mahmood, Asim Y. Ibrahim, Amani M. El Sisi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
glimepiride
nanoemulsion
inclusion complexed nanoemulgels
clove oil
xanthan
Online Access:https://www.mdpi.com/2073-4409/10/9/2404

Internet

https://www.mdpi.com/2073-4409/10/9/2404

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