Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors

Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors

Abstract Monoamine oxidases (MAOs), specifically MAO-A and MAO-B, play important roles in the breakdown of monoamine neurotransmitters. Therefore, MAO inhibitors are crucial for treating various neurodegenerative disorders, including Parkinson's disease (PD), Alzheimer’s disease (AD), and amyot...

Full description

Bibliographic Details
Main Authors: Sunil Kumar, Ratul Bhowmik, Jong Min Oh, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rasha Hamed Al‑Serwi, Hoon Kim, Bijo Mathew
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Monoamine oxidase B
ML-QSAR
PubChem fingerprints
Substructure fingerprints
1D and 2D molecular descriptors
Prediction models
Online Access:https://doi.org/10.1038/s41598-024-55628-y

Internet

https://doi.org/10.1038/s41598-024-55628-y

Similar Items