Fumaric Acids Do Not Directly Influence Gene Expression of Neuroprotective Factors in Highly Purified Rodent Astrocytes

Fumaric Acids Do Not Directly Influence Gene Expression of Neuroprotective Factors in Highly Purified Rodent Astrocytes

(1) Background: Dimethylfumarate (DMF) has been approved for the treatment of relapsing remitting multiple sclerosis. However, the mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood. Former reports suggest a neuroprotective effect o...

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Bibliographic Details
Main Authors: Kaweh Pars, Marina Gingele, Jessica Kronenberg, Chittappen K Prajeeth, Thomas Skripuletz, Refik Pul, Roland Jacobs, Viktoria Gudi, Martin Stangel
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Brain Sciences
Subjects:
glia
astrocytes
dimethylfumarate
monomethylfumarate
neuroprotection
growth factors
Online Access:https://www.mdpi.com/2076-3425/9/9/241

Internet

https://www.mdpi.com/2076-3425/9/9/241

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