Human Serum Metabolites as Potential Mediators from Type 2 Diabetes and Obesity to COVID-19 Severity and Susceptibility: Evidence from Mendelian Randomization Study

Human Serum Metabolites as Potential Mediators from Type 2 Diabetes and Obesity to COVID-19 Severity and Susceptibility: Evidence from Mendelian Randomization Study

Obesity, type 2 diabetes (T2D), and severe coronavirus disease 2019 (COVID-19) are closely associated. The aim of this study was to elucidate the casual and mediating relationships of human serum metabolites on the pathways from obesity/T2D to COVID-19 using Mendelian randomization (MR) techniques....

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Bibliographic Details
Main Authors: Chuiguo Huang, Mai Shi, Hongjiang Wu, Andrea O. Y. Luk, Juliana C. N. Chan, Ronald C. W. Ma
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
COVID-19
human serum metabolites
type 2 diabetes
obesity
Mendelian randomization
mediation analysis
Online Access:https://www.mdpi.com/2218-1989/12/7/598

Internet

https://www.mdpi.com/2218-1989/12/7/598

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