CNN3 regulates trophoblast invasion and is upregulated by hypoxia in BeWo cells.

CNN3 is an ubiquitously expressed F-actin binding protein, shown to regulate trophoblast fusion and hence seems to play a role in the placentation process. In this study we demonstrate that CNN3 levels are upregulated under low oxygen conditions in the trophoblast cell line BeWo. Since hypoxia is di...

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Bibliographic Details
Main Authors: Sarah Appel, Janina Ankerne, Jan Appel, Andre Oberthuer, Peter Mallmann, Jörg Dötsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4106885?pdf=render