Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease

Abstract Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune dysregulation, and multi-organ fibrosis. Interstitial lung disease (ILD) is a complication of SSc and a leading cause of SSc-death. The administration of hypochlorous acid (HOCl) intradermally in the mou...

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Bibliographic Details
Main Authors: Arina Morozan, Sydney Joy, Utako Fujii, Richard Fraser, Kevin Watters, James G. Martin, Inés Colmegna
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47083-y