Serum metabolomic characterization of PLA2G6-associated dystonia–parkinsonism: A case-control biomarker study

Serum metabolomic characterization of PLA2G6-associated dystonia–parkinsonism: A case-control biomarker study

IntroductionPhospholipase A2 Group VI (PLA2G6), encoding calcium-independent phospholipase A2, has been isolated as the gene responsible for an autosomal recessive form of early-onset Parkinson’s disease (namely, PARK14). Compared to idiopathic Parkinson’s disease (iPD), PARK14 has several atypical...

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Bibliographic Details
Main Authors: Chen Chen, Min-Min Lou, Yi-Min Sun, Fang Luo, Feng-Tao Liu, Su-Shan Luo, Wen-Yuan Wang, Jian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroscience
Subjects:
PLA2G6
metabolomics
early-onset parkinsonism
long chain fatty acids
serum biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.879548/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.879548/full

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