CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex

CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex

Summary: CUX1 is a homeodomain-containing transcription factor that is essential for the development and differentiation of multiple tissues. CUX1 is recurrently mutated or deleted in cancer, particularly in myeloid malignancies. However, the mechanism by which CUX1 regulates gene expression and dif...

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Bibliographic Details
Main Authors: Weihan Liu, Jeffrey L. Kurkewich, Angela Stoddart, Saira Khan, Dhivyaa Anandan, Alexandre N. Gaubil, Donald J. Wolfgeher, Lia Jueng, Stephen J. Kron, Megan E. McNerney
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Cell Reports
Subjects:
CP: Stem cell research
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724005552

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http://www.sciencedirect.com/science/article/pii/S2211124724005552

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