Remifentanil does not affect human microglial immune activation in response to pro-inflammatory cytokines

Remifentanil is a potent ultra-short acting μ-opioid analgesic drug, frequently used in anaesthesia due to its favorable pharmacodynamic and pharmacokinetic profile. It may be associated with the occurrence of hyperalgesia. Preclinical studies suggest a potential role of microglia, although the mole...

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Bibliographic Details
Main Authors: Cinzia Dello Russo, Natalia Cappoli, Elisabetta Tabolacci, Liliana Sollazzi, Pierluigi Navarra, Paola Aceto
Format: Article
Language:English
Published: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund 2023-02-01
Series:EXCLI Journal : Experimental and Clinical Sciences
Subjects:
Online Access:https://www.excli.de/index.php/excli/article/view/5667