Injectable Cell-Laden Nanofibrous Matrix for Treating Annulus Fibrosus Defects in Porcine Model: An Organ Culture Study

Injectable Cell-Laden Nanofibrous Matrix for Treating Annulus Fibrosus Defects in Porcine Model: An Organ Culture Study

Lower back pain commonly arises from intervertebral disc (IVD) failure, often caused by deteriorating annulus fibrosus (AF) and/or nucleus pulposus (NP) tissue. High socioeconomic cost, quality of life issues, and unsatisfactory surgical options motivate the rapid development of non-invasive, regene...

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Bibliographic Details
Main Authors: Evan Roebke, Diego Jacho, Oliver Eby, Sulaiman Aldoohan, Haitham Elsamaloty, Eda Yildirim-Ayan
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Life
Subjects:
annulus fibrosus
tissue regeneration
ex vivo
organ culturing
porcine model
polycaprolactone
Online Access:https://www.mdpi.com/2075-1729/12/11/1866

Internet

https://www.mdpi.com/2075-1729/12/11/1866

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