DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data

DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data

Abstract Single-cell RNA sequencing (scRNA-seq) offers new opportunities to study gene expression of tens of thousands of single cells simultaneously. We present DeepImpute, a deep neural network-based imputation algorithm that uses dropout layers and loss functions to learn patterns in the data, al...

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Bibliographic Details
Main Authors: Cédric Arisdakessian, Olivier Poirion, Breck Yunits, Xun Zhu, Lana X. Garmire
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Biology
Subjects:
RNA-seq
Single-cell
Imputation
Deep learning
Machine learning
Neural network
Online Access:http://link.springer.com/article/10.1186/s13059-019-1837-6

Internet

http://link.springer.com/article/10.1186/s13059-019-1837-6

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