NUSAP1 promotes pancreatic ductal adenocarcinoma progression by drives the epithelial-mesenchymal transition and reduces AMPK phosphorylation

NUSAP1 promotes pancreatic ductal adenocarcinoma progression by drives the epithelial-mesenchymal transition and reduces AMPK phosphorylation

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, and its molecular mechanisms are unclear. Nucleolar and spindle-associated protein 1 (NUSAP1), an indispensable mitotic regulator, has been reported to be involved in the development of several types of tumors. The bio...

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Bibliographic Details
Main Authors: Yuan Liu, Rong Tang, Qing-Cai Meng, Si Shi, Jin Xu, Xian-Jun Yu, Bo Zhang, Wei Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Pancreatic ductal adenocarcinoma
Differentially expressed genes
Functional enrichment analysis
Protein‒protein interaction
Survival analysis
Online Access:https://doi.org/10.1186/s12885-024-11842-5

Internet

https://doi.org/10.1186/s12885-024-11842-5

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