Assessing the quality of evidence on safety: specifications for application and suggestions for adaptions of the GRADE-criteria in the context of preparing a list of potentially inappropriate medications for older adults

Assessing the quality of evidence on safety: specifications for application and suggestions for adaptions of the GRADE-criteria in the context of preparing a list of potentially inappropriate medications for older adults

Abstract Background Systematic reviews that synthesize safety outcomes pose challenges (e.g. rare events), which raise questions for grading the strength of the body of evidence. This is maybe one reason why in many potentially inappropriate medication (PIM) lists the recommendations are not based o...

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Bibliographic Details
Main Authors: Tim Mathes, Nina-Kristin Mann, Petra Thürmann, Andreas Sönnichsen, Dawid Pieper
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Medical Research Methodology
Subjects:
Evidence synthesizes
systematic reviews
potentially inadequate medications
PIM-List
GRADE
Level of Evidence
Online Access:https://doi.org/10.1186/s12874-022-01715-5

Internet

https://doi.org/10.1186/s12874-022-01715-5

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