Orally administered melatonin prevents lipopolysaccharide-induced neural tube defects in mice.

Orally administered melatonin prevents lipopolysaccharide-induced neural tube defects in mice.

Lipopolysaccharide (LPS) has been associated with adverse pregnant outcomes, including fetal demise, intra-uterine growth restriction (IUGR), neural tube defects (NTDs) and preterm delivery in rodent animals. Previous studies demonstrated that melatonin protected against LPS-induced fetal demise, IU...

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Bibliographic Details
Main Authors: Lin Fu, Zhen Yu, Yuan-Hua Chen, Mi-Zhen Xia, Hua Wang, Cheng Zhang, Fang-Biao Tao, De-Xiang Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4242665?pdf=render

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http://europepmc.org/articles/PMC4242665?pdf=render

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