Epigenetic regulation of human WIF1 and DNA methylation situation of WIF1 and GSTM5 in urothelial carcinoma

WNT inhibitory factor 1 (WIF1) is known to function as a tumor suppressor gene; it inhibits oncogene activation by preventing WNT signaling. This study investigated the epigenetic regulation of WIF1 gene in bladder cancer. We observed a positive relationship between WIF1 mRNA expression and survival...

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Bibliographic Details
Main Authors: Cheng-Huang Shen, Pei-Yu Li, Shou-Chieh Wang, Sin-Rong Wu, Chih-Yu Hsieh, Yuan-Chang Dai, Yi-Wen Liu
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023032115