Computational methods for chromosome-scale haplotype reconstruction
Abstract High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid genomes, and metagenomes provide important insights into genetic variation associated with disease and biodiversity. However, whole-genome short read sequencing does not yield haplotype information spanning whol...
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-021-02328-9 |