Protein arginine methyltransferase 3 inhibits renal tubulointerstitial fibrosis through asymmetric dimethylarginine

Protein arginine methyltransferase 3 inhibits renal tubulointerstitial fibrosis through asymmetric dimethylarginine

Mammalian protein arginine methyltransferase 3 (PRMT3) catalyzes the monomethylation and dimethylation of the arginine residues of proteins. The role of PRMT3 in renal fibrosis is currently unknown. We aimed to study the role of PRMT3 in renal fibrosis and explored its underlying mechanisms. Quantit...

Full description

Bibliographic Details
Main Authors: Yanzhe Wang, Ming Wu, Feng Yang, Junyan Lin, Li Zhang, Meijie Yuan, Dongping Chen, Bo Tan, Di Huang, Chaoyang Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
ADMA
fibrosis
arginine methyltransferase
chronic kidney disease
obstructive nephropathy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.995917/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.995917/full

Similar Items