Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation

Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation

Summary: Zygotic genome activation (ZGA) initiates transcription in early embryogenesis and requires extensive chromatin remodeling, including rapid incorporation of the histone variant H3.3. The distinct sources of H3.3 from paternal and maternal alleles (paH3.3 and maH3.3) complicate tracking thei...

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Bibliographic Details
Main Authors: Jiaming Zhang, Xuanwen Li, Qi Zhao, Jingzhang Ji, Hongdi Cui, Weibo Hou, Xinyu Wang, Entong Song, Songling Xiao, Shukuan Ling, Shaorong Gao, Xiaoyu Liu, Duancheng Wen, Qingran Kong
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Molecular biology
CP: Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014992

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http://www.sciencedirect.com/science/article/pii/S2211124724014992

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