Potential Antitumor Effect of α-Mangostin against Rat Mammary Gland Tumors Induced by LA7 Cells

Potential Antitumor Effect of α-Mangostin against Rat Mammary Gland Tumors Induced by LA7 Cells

In this study, the chemotherapeutic effect of α-mangostin (AM) was assessed in rats injected with LA7 cells. Rats received AM orally at 30 and 60 mg/kg twice a week for 4 weeks. Cancer biomarkers such as CEA and CA 15-3 were significantly lower in AM-treated rats. Histopathological evaluations showe...

Full description

Bibliographic Details
Main Authors: Mohamed Yousif Ibrahim, Najihah Mohd Hashim, Fatima Abdelmutaal Ahmed Omer, Muhammad Salisu Abubakar, Hoyam Adam Mohammed, Suzy Munir Salama, Soher Nagi Jayash
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
α-mangostin
mammary cancer
LA7 cells
apoptosis
immunohistochemistry
antioxidant
Online Access:https://www.mdpi.com/1422-0067/24/12/10283

Internet

https://www.mdpi.com/1422-0067/24/12/10283

Similar Items