HLA-DRB1 is associated with cefaclor-induced immediate hypersensitivity

HLA-DRB1 is associated with cefaclor-induced immediate hypersensitivity

Background: Drug-induced hypersensitivity such as anaphylaxis is an important cause of drug-related morbidity and mortality. Cefaclor is a leading cause of drug induced type I hypersensitivity in Korea, but little is yet known about genetic biomarkers to predict this hypersensitivity reaction. We ai...

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Main Authors: So-Young Park, MD, PhD, So Young Park, MD, PhD, Sujin Seo, BS, Hyouk-Soo Kwon, MD, PhD, Seung-Hyun Kim, PhD, Sae-Hoon Kim, MD, PhD, Hye-Kyung Park, MD, PhD, Yoon-Seok Chang, MD, PhD, Cheol-Woo Kim, MD, PhD, Byung Jae Lee, MD, PhD, Hae-Sim Park, MD, PhD, You Sook Cho, MD, PhD, Heung-Bum Oh, PhD, David A. Ostrov, PhD, Sungho Won, PhD, Tae Bum Kim, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:World Allergy Organization Journal
Subjects:
Drug hypersensitivity
Whole exome sequencing
Immediate hypersensitivity
Cephalosporin
Cefaclor
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455124000322

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http://www.sciencedirect.com/science/article/pii/S1939455124000322

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