Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay

The issue of antibody cross-reactivity is of central importance in immunology, and not least in protective immunity to Plasmodium falciparum malaria, where key antigens show substantial allelic variation (polymorphism). However, serological analysis often does not allow the distinction between true...

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Bibliographic Details
Main Authors: Henriette Hoffmann-Veltung, Nsoh Godwin Anabire, Michael Fokuo Ofori, Peter Janhmatz, Niklas Ahlborg, Lars Hviid, Maria del Pilar Quintana
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/79245