Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis
A fundamental process in the development and progression of heart failure is fibrotic remodeling, characterized by excessive deposition of extracellular matrix proteins in response to injury. Currently, therapies that effectively target and reverse cardiac fibrosis are lacking, warranting novel ther...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Jezik: | English |
| Izdano: |
Frontiers Media S.A.
2022-03-01
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| Serija: | Frontiers in Cardiovascular Medicine |
| Teme: | |
| Online dostop: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.854314/full |