The impact of serum protein binding on bacterial killing of minocycline

Objectives: Minocycline is increasingly used clinically for treating infections due to multidrug resistant bacteria. We previously reported that the serum protein binding of minocycline atypically correlated with total concentration using microdialysis, but the therapeutic implications of this findi...

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Bibliographic Details
Main Authors: Li-Xia Xie, Jian Zhou, Kimberly R. Ledesma, Paul R. Merlau, Vincent H. Tam
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716519303030