Knockdown of Porf-2 restores visual function after optic nerve crush injury

Abstract Retinal ganglion cells (RGCs), the sole output neurons in the eyes, are vulnerable to diverse insults in many pathological conditions, which can lead to permanent vision dysfunction. However, the molecular and cellular mechanisms that contribute to protecting RGCs and their axons from injur...

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Bibliographic Details
Main Authors: Di Chen, Yi-Yu Sun, Lai-Yang Zhou, Xu Han, Shuo Yang, Fei-Yang Hong, Yuan Yuan, Xiao-Hua Wu, Guo-Hui Huang, Yuan-Chi Cheng, Ju Huang, Dong-Fu Feng
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06087-2