Exposure to a High-Fat Diet during Early Development Programs Behavior and Impairs the Central Serotonergic System in Juvenile Non-Human Primates

Perinatal exposure to maternal obesity and high-fat diet (HFD) consumption not only poses metabolic risks to offspring but also impacts brain development and mental health. Using a non-human primate model, we observed a persistent increase in anxiety in juvenile offspring exposed to a maternal HFD....

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Bibliographic Details
Main Authors: Jacqueline R. Thompson, Jeanette C. Valleau, Ashley N. Barling, Juliana G. Franco, Madison DeCapo, Jennifer L. Bagley, Elinor L. Sullivan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00164/full